Cardinals Vs. Lions Betting Odds And Preview — Can The Lions Cover The Spread Again?

The point spread on the Cardinals-Lions game this weekend is right where it should be with Arizona a nearly two-touchdown favorite against Detroit. Why so much? Despite their recent loss, the Cardinals are one of the best teams in the NFL. As for the Detroit Lions, well, they are not.

However, the Lions have played well enough to cover the spread quite a few times this season. Could they do it again? Here are all the betting odds for Sunday’s game.

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Cardinals Vs. Lions Betting Odds

Sportsbook Point Spread Moneyline Total    
DraftKings Cardinals -12 (-110)
Lions +12 (-110)
Cardinals -575
Lions +410
Over 47 (-115)
Under 47 (-105)
BetMGM Cardinals -13.5 (-105)
Lions +13.5 (-115)
Cardinals -750
Lions +525
Over 47.5 (-110)
Under 47.5 (-110)
Caesars Cardinals -13 (-115)
Lions +13 (-105)
Cardinals -800
Lions +550
Over 47.5 (-110)
Under 47.5 (-110)
BetRivers Cardinals -13 (-108)
Lions +13 (-113)
Cardinals -625
Lions +500
Over 47.5 (-109)
Under 47.5 (-112)

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No DeAndre Hopkins, No Problem?

As much as fans enjoy watching their Cardinals at home, they may like seeing their team go on the road even more. Arizona has been unstoppable on the road this season going 7-0 and winning by 10+ points in every game. With the injuries piling up this week, that streak could be in jeopardy.

The team announced Wednesday that WR DeAndre Hopkins will be out for the remainder of the regular season due to a knee sprain suffered against the Rams. Hopkins had returned the week prior against Chicago after missing the previous three games with a different injury.

There is a chance RB James Conner could miss the game, as well. He appeared to injure his ankle on the final play of the Rams game. His status is day-to-day, but the team may not push Conner to play if RB Chase Edmonds can go.

Injuries are doing a number on the defense, as well. CB Robert Alford sat out Wednesday’s practice with a pectoral injury suffered against the Rams last week. DT Leki Fotu, DT Zach Kerr, and DT Corey Peters also sat out Wednesday.

It is too early to say who will miss the game (other than Hopkins). So far, the Cardinals are not one of several teams hit hard by COVID-19 this week. Should Arizona lose anyone else to an injury or COVID-19 later in the week, Lions fans may start thinking about an outright upset instead of just covering the spread.

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Injuries And COVID Taking A Toll On The Lions

Injuries are doing a number to the Arizona roster this week, but injuries and COVID-19 are doing an even bigger one on the Lions’ roster. Seven players were out last week due to COVID. While C Evan Brown has come off, CB Nickell Robey-Coleman was added to the Tuesday list.

It is unclear if anyone else will get off the list in time for Sunday’s game.

On the injury front, five players missed practice Wednesday: TE T.J. Hockenson, RB D’Andre Swift, OL Jonah Jackson, LB Alex Anzalone, and LB Julian Okwara. CB Jerry Jacobs is out for the remainder of the season after tearing his ACL against the Broncos.

Missing a Wednesday practice does not mean someone will miss the game, but it does mean you should monitor their status as the week progresses.

For Swift, last week made it two in a row for him. With RB Jamaal Williams on the COVID list, the team turned to a running back fresh off the practice squad, Craig Reynolds. If Williams and Swift cannot go, the Cardinals can probably look forward to a heavy dose of Reynolds this week.

The Lions’ defense would struggle to keep up with the Cardinals even if every starter was healthy. With several players sitting out practice and still on the COVID list, it could get ugly early.

Betting Analysis

Last week was the first time in a month that the Lions failed to cover the spread. With the Cardinals being down at least one key player and possibly more, maybe the Lions can be more competitive than the 13.5-point spread indicates.

Don’t count on it.

The Cardinals have played well without their best players, but the Lions have not. Arizona may be down a player or two in this game, but the Lions will likely be without several. Detroit will probably not keep this one close. However, don’t bank on this being a high-scoring game.

Our Pick: Under 47.5

About the Author

Travis Pulver

Travis Pulver is a lifelong football fan, which he believes comes naturally as he hails from the football-crazy state of Texas. His love of sports, over the years, has grown to include basketball, baseball, rugby, and golf. Currently, life finds him in Indiana with his wife and two kids.